Marvin OnumonuData from Direct365 found workers in Blaenau Gwent were over 14 times more likely to have a workplace injury than those in London.
Research revealed that Blaenau Gwent saw 479 injuries per 100,000 employees, more than double the national average.
Argyll and Bute followed at 469 per 100,000, then Boston, Knowsley, and Bolsover, all with over 440 injuries per 100,000 workers.
In contrast, the City of London was found to be the safest place to work with 34 injuries per 100,000 employees.
Southwark and Watford also recorded low rates, at 59 and 76 respectively, compared to the UK average of 209 per 100,000.
The report found fractures and sprains made up 58% of non-fatal injuries, with 18,516 fractures and 15,804 sprains or strains.
There were 1,413 cases of burns, 706 cases where workers lost consciousness, 543 amputations, 132 cases where workers lost or reduced their sight, and 111 reports of internal organ damage.
The deadliest industries were forestry and logging, with a fatal injury rate of 10.43 per 100,000 employees.
This was followed by agriculture, forestry and fishing at 8.23, waste collection and disposal at 2.70, construction at 1.66, and manufacturing at 0.42.
The UK average fatality rate was 0.37 per 100,000 employees.
Karl Bantleman at Direct365 said: “While a worker’s physical safety should never be determined by their postcode, the data reveals a worrying ‘workplace safety lottery’ across the UK.
“While workers in the City of London remain relatively safe from injury, those in industrial hubs like Blaenau Gwent are slipping through the cracks with injury rates fourteen times higher.
“With 10 amputations every week and over 100 workers losing their sight last year, the human cost of these accidents is staggering.”
Bantleman added: “These ‘shock’ injuries are permanent and life-altering and business owners cannot afford to wait for a tragedy before reviewing their physical safety protocols.
“To help protect staff and ensure workplace safety standards are met, business owners must ensure all machinery is properly guarded and maintained, provide high-quality PPE for all high-risk tasks, and, most importantly, ensure that Risk Assessments are reviewed immediately whenever a workplace process or environment changes.”
